AspireSR™

VNS Therapy can lead to fewer seizures, shorter seizures and better recovery after seizures.

AspireSR™ VNS Therapy device
AspireSR™ detects and responds to rapid increases in heart rate which may be associated with a seizure

AspireSR™ detects and responds to rapid increases in heart rate, which may be associated with a seizure1

In clinical trials, over 60% of seizures treated ended during automatic stimulation.

The closer the stimulation to seizure onset, the shorter the seizure duration2

VNS Therapy controls seizures in 3 ways

Normal Mode - Preventative

Normal Mode

Helps Prevent seizures

Stimulation is delivered at regular intervals all day, every day, to help prevent seizures1

Responsive* AutoStim Mode

AutoStim Mode

Responds to rapid increases in heart rate*

An extra dose of therapy is automatically delivered at the sign of a rapid increase in heart rate, which may be associated with seizures1,3,4

*Only available in models 106, 1000, and 1000-D

On-Demand Magnet Mode

Magnet Mode

Delivers On-Demand Treatment

Stimulation is manually delivered by swiping the included VNS Therapy™  magnet over the generator to help stop or shorten a seizure once it starts1

VNS Therapy™ Can Provide Improvements in Seizure Control*

VNS Therapy™ Can De-Intensify Seizures and Provide Improvements in Seizure Control6*

59% reported ≥ 50% reduction in seizures

41% reported ≥ 80% reduction in seizures 

* Data is from devices with AutoStim Mode enabled, which is only available in models 106, 1000, and 1000-D.

VNS Therapy™ can reduce the impact of seizures and can enable improved post-ictal recovery

VNS Therapy™ can reduce the impact of seizures and can help improve post-ictal recovery

Clinically meaningful improvement from baseline8

 

AspireSR™ is shown to improve quality of life

AspireSR™ is shown to improve quality of life2

Clinically meaningful and statistically significant improvements in overall QOL were seen at 3 months and continued to improve over time.

AspireSR™ - Advancing the treatment of drug-resistant epilepsy

AspireSR - Advancing the treatment of drug-resistant epilepsy

  • Provides demonstrated efficacy and safety of VNS Therapy
  • May terminate seizures by delivering automatic stimulation when a seizure occurs
  • May reduce seizure duration and seizure severity and improve post-ictal recovery
  • Improves quality of life

AspireSR™ Technical Sheet

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MRI Safety

The latest VNS Therapy™ technology with expanded MRI access allows patients to obtain quality MRI scans

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References
1. VNS Therapy SystemTM Epilepsy Physician’s Manual (US), March 2023, LivaNova USA, Inc. Houston, TX. 2. Data on file, LivaNova, USA Inc., Houston, TX. 3. Fisher RS, Afra P, Macken M, et al. Neuromodulation. 2016;19:188-195. 4. Hirsch M, Altenmüller DM, Schulze-Bonhage A. Epilepsia. 2015;56(10):1639-1647. 5. Datta P, Galla KM , Sajja K, et al. Epilepsy Behav. 2020;111:107280.

VNS Therapy Safety Profile

The most common side effects of VNS Therapy include:

Hoarseness
Shortness of breath
Sore throat
Coughing

These side effects generally only occur during stimulation and usually decrease over time.

Infection is the most common side effect of the procedure.

You can find more safety information here.