Patients & Caregivers Healthcare Providers

Empower your patients with drug-resistant epilepsy to live fuller lives and achieve their full potential
Resources & Support

Resources & Support

Discover the resources you need to make the most of VNS Therapy, including product training, expert healthcare provider perspectives, practice support, and patient education

Learn More
VNS Therapy™ for Pediatric Patients

VNS Therapy™ for Pediatric Patients

Examine the efficacy, safety, and quality of life benefits VNS Therapy™ can offer your pediatric patients with drug-resistant epilepsy

Learn More
VNS Therapy™ for Adult Patients

VNS Therapy™ for Adult Patients

Explore the benefits VNS Therapy™ can offer your adult patients with drug-resistant epilepsy, including improvements in seizure control and quality of life

Learn More
Real-Life Stories

Real-Life Stories

Watch real-life testimonials about how VNS Therapy has provided life-changing seizure control for adult and pediatric patients with drug-resistant epilepsy

Learn More
The VNS Therapy System is indicated for use as an adjunctive therapy in reducing the frequency of seizures in patients 4 years of age and older with partial onset seizures that are refractory to antiepileptic medications.

The nerve to move beyond medication.

When managing drug-resistant epilepsy (DRE), medications alone won’t be enough to help your patients achieve seizure control or provide improved quality of life. As soon as you suspect DRE, consider non-drug treatment options and speak to your patients about them. The sooner you act, the more likely you are to mitigate the serious consequences of DRE.

Understanding the treatment goals for DRE

Goals for patients with DRE include1:
Improving long-term seizure control

Improving long-term seizure control

  • Fewer, shorter, less severe seizures
  • Improved postictal recovery
Minimizing treatment-related side effects

Minimizing treatment-related side effects
Ensuring treatment adherence

Ensuring treatment adherence
Maximizing quality of life

Maximizing quality of life

Effective management of DRE requires a proactive treatment strategy

VNS Therapy™ is a well established neuromodulation therapy in use for DRE patients and has been shown to offer quality-of-life benefits that can help patients overcome obstacles they face in everyday life. 
VNS Therapy stimulates the vagus nerve, sending mild electrical pulses to the brain to help prevent seizures

VNS Therapy stimulates the vagus nerve, sending mild electrical pulses to the brain to help prevent seizures2
Uses an implantable generator and lead and can be programmed to fit the needs of a patient's individualized treatment strategy

Uses an implantable generator and lead and can be programmed to fit the needs of each patient2
Unlike invasive brain surgeries, VNS Therapy involves a short outpatient procedure that usually takes 1 to 2 hours

Unlike invasive brain surgeries, VNS Therapy involves a short outpatient procedure that usually takes 1 to 2 hours2
Treatment is delivered automatically, maximising adherence for optimal seizure control

Treatment is delivered automatically, maximizing adherence for optimal seizure control2

VNS Therapy™ controls seizures in three ways
Normal Mode

Preventative

Normal Mode

Helps prevent seizures by delivering treatment at regular intervals all day, every day2
Responsive mode (Austostim)

Responsive

AutoStim Mode*

Helps stop or shorten a seizure by responding to a rapid increase in heart rate, a potential seizure biomarker2,3

*Only available in models 106, 1000, and 1000-D
Magnet Mode (On-Demand)

On-Demand

Magnet Mode

Helps stop or shorten a seizure once it starts by passing the included VNS Therapy Magnet over the generator2

VNS Therapy™ in action

Trust in 3 decades of real-world experience

VNS Therapy™ is built on a legacy that spans over 3 decades.

With over 1.5 million patient-years of treatment experience, it’s easy to see why so many physicians choose to treat DRE with VNS Therapy.
prescribed device for treating DRE4

prescribed device for treating DRE5
Only DRE neurostimulation therapy indicated to treat children as young as 4 years old

Only DRE neurostimulation therapy indicated to treat children as young as 4 years old2
125,000+ patients treated, including 35,000 children4

125,000+ patients treated, including 35,000 children5

75% of patients chose to replace their device at the end of service5

Epilepsy (US) – The VNS Therapy System is indicated for use as an adjunctive therapy in reducing thefrequency of seizures in patients 4 years of age and older with partial onset seizures that are refractory to antiepileptic medications.
 

VNS Therapy™ Safety Profile

The most common side effects of VNS Therapy include:
Hoarseness
Shortness of breath
Sore throat
Coughing
These side effects generally only occur during stimulation and usually decrease over time.
Infection is the most common side effect of the procedure.
You can find more safety information here.

References: 1. Boon P, Ryvlin P, Wheless JW, et al. European Neurological Review. 2015;10(2):171-175. 2. VNS Therapy System Epilepsy Physician’s Manual (US), September 2023, LivaNova USA, Inc. Houston, TX. 3. Fisher RS, Afra P, Macken M, et al. Neuromodulation. 2016;19:188-195. 4. Data on file, LivaNova USA, Inc., Houston, TX. 5. Data on file, LivaNova USA, Inc., Houston, TX. 2021.

© 2025 LivaNova PLC. All Rights Reserved.

Top

Choose a country

Australia Flag
Australia
 Brazil Flag
Brazil
 Canada Flag
Canada
 Colombia Flag
Colombia
 Germany Flag
Germany
 Italy Flag
Italy
 Netherlands Flag
Netherlands
 Portugal Flag
Portugal
 Spain Flag
Spain
Japan
 Sweden Flag
Sweden
 United Kingdom Flag
United Kingdom
 United States Flag
United States
For ALL other countries, please click here.