AspireSR™

The change from regular to responsive VNS Therapy^TM showed a reduction of seizure frequency

Based on the McHugh Classification of patients receiving VNS Therapy:

12 out of 19 patients (41%) who had less than 50% seizure reduction with regular VNS Therapy reported more than 50% seizure reduction with responsive VNS Therapy following a battery change.

This study was a non-controlled retrospective analysis of data where the seizure reporting is an interpretation of patients and carers.

^{*Conventional VNS Therapy in this article refers to models before AspireSR without the cardiac based seizure detection and closed loop stimulation. **Responsive VNS Therapy in this article refers to AspireSR model.}

*Responsive VNS Therapy™ refers to VNS Therapy devices with AutoStim Mode enabled. Available in models 106 and 1000, 1000-D 

^†Individual study example (N=28/46). Results may vary.

References
1. Elliott R.E. et al. Epilepsy & Behavior, 20 (2011) 57–63 2. VNS Therapy System™ Epilepsy Physician’s Manual, January 2021, LivaNova, Houston, TX. 3. Orosz I. et al. Epilepsia, 55(10):1576–1584, 2014 4. Data on file, LivaNova, Inc., Houston, TX.  5. Hamilton, P., et al. (2018) Seizure 58:120-126.  16. VNS Therapy™ System Epilepsy Physician’s Manual April 2021, 76-0000-5600/8 (OUS)